This study attempted to determine the adjustment problems and the coping techniques of the middle-aged Chinese missionaries in the Philippines. Likewise, it proposed a guidance intervention program for middle-aged Catholic Chinese missionaries in the Philippines. The hypotheses tested states that the middle-aged Catholic Chinese missionaries in the Philippines do not differ in their adjustment problems and coping techniques when grouped according to age, educational qualification, present apostolate, and length of stay. The researcher used the descriptive/comparative method in answering the research problems. Questionnaires in midlife ajustment problems and coping techniques were administered to gather data. The t-test of independece and the one-way ANOVA were computed to test the hypotheses. The Scheffe method was used to test which pair of groupings showed a significant difference. The findings revealed that the respondents occassionally had adjustment problems when they were grouped according to age, educational qualification, present apostolate, and length of stay. Most of the times the respondents used Problem Management and Appraisal techniques of coping to cope with their adjustment problems when they were grouped accoroding to age, educational qualification, present apostolate, and length of stay. Age, educational qualification, present apostolate, and length of stay are not factors of adjustment problems in this study. Also, age, educational qualification, and length of stay are not factors of coping techniques. Only the present apostolate showed being a significant factor in coping techniques in favor of those who are working. In the light of the findings presented the proposed guidance intervention program for the middle-aged Chinese missionaries in the Philippines was developed. From the results presented, the following consclusions were drawn: 1) the respondents occassionally had adjustment problems; 2) the coping techniques most of the times they used Problem Management and Appraisal Techniques; 3) age, educational qualification, present apostolate, and length of stay are not factors of adjustment problems in this study; 4) age. educational qualification, and legnth of stay are not factors of coping techniques; and 5) working vs. studying and working are significant factors.